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Stability of insulin in plga nanoparticles after complexation with protamine

  • At: 2005 FIP Congress in Cairo (Egypt)
  • Type: Poster
  • By: CHEN, Yan (Curtin University of Technology, School of Pharmcy, Perth, Australia)
  • Co-author(s): Wang (Curtin University of Technology, PERTH, Australia)
    Benson (Curtin University of Technology, PERTH, Australia)
  • Abstract:

    Aims: To investigate the effect of complexation on the stability of insulin in biodegradable nanoparticles of poly (D, L-lactic-co-glycolic acid) (PLGA). Methods: Bovine insulin was incorporated into PLGA nanoparticles by a solvent evaporation and a solvent diffusion method following its complexation with protamine. A stability-indicating high..

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Last update 4 October 2019

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