Getting past the blood-brain barrier to improve the treatment of diseases of the central nervous system
- At: 2012 FIP Congress in Amsterdam (the Netherlands)
- Type: Presentation
- By: HAMMARLUND-UDENAES, Margareta (Uppsala University, Department of Pharmaceutical Biosciences, Uppsala, Sweden)
AbstractThe blood-brain barrier (BBB) is made up of the endothelial cells of the capillaries in the brain. Apart from its tight junctions it also has efflux transporters like P-glycoprotein that keep many drugs out of the brain, and other uptake transporters that promotes uptake of some drugs into the brain. Knowledge about the role of drug.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.