Optimising the impact of uptake and efflux transporters in cancer chemotherapy
- At: 2012 FIP Congress in Amsterdam (the Netherlands)
- Type: Presentation
- By: SCHELLENS, Jan (The Netherlands Cancer Institute, Clinical Pharmacology, Amsterdam, Netherlands)
- Co-author(s): Beijnen, J.H. (Slotervaart Hospital, Amsterdam, Netherlands)
Huitema, A.D.R. (Slotervaart Hospital, Amsterdam, Netherlands)
Nuijen, B. (Slotervaart Hospital, Amsterdam, Netherlands)
Oral administration of anticancer drugs is most often preferred over intravenous administration, as it is convenient for patients, prevents hospitalization and reduces costs of the therapy. However, the use of oral administration is often hampered by low oral bioavailability for instance of the taxanes, paclitaxel and docetaxel. Limited oral.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.