Design and in-vitro evaluation of alginate hydrogel particles of gliclazide for oral controlled release: effect of polymer type.

• In: Industrial Pharmacy Section - Poster Session
• At: Cairo (Egypt) (2005)
• Type: Poster
• Poster code: IPS-P-026
• By: GHORAB, Mamdouh (College of pharmacy, Suez Canal Univ., Pharmaceutics, Cairo, Egypt)
• Co-author(s): Abdel salam (Medical union pharmaceutical co., ABU-SULTAN, ISMAILIA, Egypt)
  Abdel moaty (Medical union pharmaceutical co., ABU-SULTAN, ISMAILIA, Egypt)
  
• Abstract:

  Gliclazide,an effective antidiabetic drug, entrapped within gel microbeads using sodium alginate and systems containing mixtures of sodium alginate and various polymers were obtained by Orifice-Ionic gelation method. encapsulation efficiencies, bead size and drug release profile were evaluated. Increase in encapsulation efficiencies for the..

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