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Physicochemical characterization and in- vivo evaluation of pioglitazone solid dispersions

  • In: Bioavailability/Bioequivalence Posters
  • At: Hyderabad (India) (2011)
  • Type: Poster
  • Poster code: BB-P-06
  • By: PANDIT, Vinay (Al-Ameen College of Pharmacy, Bangalore, India)
  • Co-author(s): Pai, Roopa S (Al-Ameen College of Pharmacy, Bangalore, India)
    Kumar, Sunil (Al-Ameen College of Pharmacy, Bangalore, India)
    Suresh, Sarasija (National Institute of Pharmaceutical Education and Research, Mohali, Punjab, India)
  • Abstract:

    Pioglitazone, a thiazolidinedione derivative with insulin sensitizing effect used in type II diabetes. Though has high permeability, exhibits dissolution rate limited absorption due to poor aqueous solubility. This in turn results in delayed onset that might have negative impact on subtherapeutic plasma drug levels leading to failure of..

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Last update 4 October 2019

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