Design, synthesis and pharmacological evaluation of celecoxib analogues
- At: 2011 FIP Congress in Hyderabad (India)
- Type: Poster
- By: MUHAMMED, Shahin (Acharya & B.M Reddy College of Pharmacy, Bangalore, India)
- Co-author(s): Das, Amit Kumar (Acharya & B.M Reddy College of Pharmacy, Bangalore, India)
Celecoxib is a selective COX-2 inhibitor, which has got fewer side effects compared to COX-1 inhibitors. Aim of the present study was to design, synthesize and evaluate some celecoxib analogues for their anti-inflammatory, anti-convulsant and depressant activities. Chalcone was synthesized by Claisen Schmidt condensation reaction from acetophenone .. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.