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Insilico design and synthesis of novel thiadiazolo and oxadiazolo pyrrolidine carboxamides as enoyl acyl carrier protein reductase inhibitors

  • At: 2011 FIP Congress in Hyderabad (India)
  • Type: Poster
  • By: GEORGE, Sonia (College of Pharmacy, Sri Ramakrishna Institute of Paramedical Sciences, Coimbatore, India)
  • Co-author(s): Ravi, T.K (College of pharmacy, Sri ramakrishna institute of paramedical sciences, Coimbatore, India)
  • Abstract:

    Tuberculosis is one among the dreadful diseases affecting millions of people worldwide.Enoyl Acyl Carrier Protein (ACP) reductase is one of the target enzyme involved in the FASII pathway of cell wall synthesis in mycobacterium species. A novel attempt was made in achieving direct Enoyl ACP reductase inhibitors which do not require Kat G..

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Last update 4 October 2019

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