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Simvastatin reverses cyclosporin a-induced vascular dysfunction in male rats: a biochemical, pharmacological and histopathological study

  • At: 2005 FIP Congress in Cairo (Egypt)
  • Type: Poster
  • By: HELMY, Mai (Faculty of Pharmacy, Alexandria, PHARMACOLOGY, Alexandria, Egypt)
  • Co-author(s): Abdel-Galil (Faculty of Pharmacy, Univ. of Alexandria, ALEXANDRIA, Egypt)
    El Sawy (Faculty of Pharmacy, Univ. of Alexandria, ALEXANDRIA, Egypt)
    Saad (Faculty of Pharmacy, Univ. of Alexandria, ALEXANDRIA, Egypt)
    Omar (Faculty of Pharmacy, Univ. of Alexandria, ALEXANDRIA, Egypt)
  • Abstract:

    Cyclosporin A (CyA) is the immunosuppressant most frequently used in transplant surgery and in the management of autoimmune diseases. CyA-induced oxidative stress together with dyslipidemia have been implicated in the pathogenesis of vascular dysfunction associating CyA therapy. The present study investigated the possible protective effect of..

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Last update 4 October 2019

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