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The stereoselective effects of amiodarone on the pharmacokinetics of racemic metoprolol in cardiac arrhythmia patients

  • At: 2004 FIP Congress in New Orleans (USA)
  • Type: Poster
  • By: TACHIBANA, Kanako (Osaka Univ. of Pharmaceutical Sciences, Clinical Pharmacology & Pharmacokinetics, Osaka, Japan)
  • Co-author(s): Fukumoto (Niigata Univ. of Pharm., Japan)
    Ueno (Niigata Univ. of Pharm., Japan)
    Komamura (National Cardiovascular Center, Japan)
    Kamakura (National Cardiovascular Center, Japan)
    Kitakaze (National Cardiovascular Center, Japan)
    Nishihori (Osaka Univ. of Pharmaceutical Sciences, OSAKA, Japan)
    Hirotani (Osaka Univ. of Pharmaceutical Sciences, OSAKA, Japan)
    Tanaka (Osaka Univ. of Pharmaceutical Sciences, OSAKA, Japan)
  • Abstract:

    Aims: Recently, amiodarone (AMD) has shifted from an agent of last recourse to that of first-line therapy in antiarrhythmic therapy, and its popularity has further increased by its rapidly growing use in the management of refractory atrial arrhythmias. However, AMD has unique pharmacokinetic properties and pharmacokineic interactions with various..

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Last update 4 October 2019

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