Formulation, pharmacokinetics and clinical evaluation of nicardipine hydrochloride sustained release floating tablets
- At: 2005 FIP Congress in Cairo (Egypt)
- Type: Poster
- By: SABRI, Nagwa ali (Faculty of Pharmacy Ain shams university, Clinical pharmacy, Cairo, Egypt)
The aim of this study is to evaluate the prepared floating tablets of nicardipine HCl (NC)and determination of its pharmacokinetic parameters and hypotensive effect compared with a standard commercial capsules.Three hydrophilic polymers;NaCMC, HPMC and Avicel in combination with CO2 generating mixture(NaHCO3and anhydrous citric acid in the ratio.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.