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Preparation of solid dispersion for pranlukast hydrate and hydroxypropylmethylcellulose system using a twin screw extruder

  • At: 2005 FIP Congress in Cairo (Egypt)
  • Type: Poster
  • By: YASUI, Shinichiro (Mijo.Univ, Nagoya, Japan)
  • Co-author(s): Yonezawa (Meijo University, NAGOYA, Japan)
    Sunada (Meijo University, NAGOYA, Japan)
  • Abstract:

    Introduction

    The solid dispersion method, by which a drug is dispersed in a carrier to makeit amorphous, is one of the pharmaceutical approaches most commonly employedto increase bioavailability of poorly water soluble drugs. A pressurization/knead- ing/extruding method using a twin screw extruder is one of the methods used to facilitate solid ..

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Last update 4 October 2019

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