Prediction and quality control of drug release from tablets using near infrared spectroscopy

• At: 2008 FIP Congress in Basel (Switzerland)
• Type: Presentation
• By: TERADA, Katsuhide (Toho University, Funabashi, Japan)
• Co-author(s): Ito, Masatomo (Daiichi Sankyo Co.,Ltd, Japan)
  
• Abstract:

  A comparison between dissolution profiles by using a dissolution apparatus and the NIR spectrum was performed for controlled release bi-layer tablets containing acetaminophen. Taking into consideration of the variation of tabletting process, tablets were prepared with fifteen different conditions. The variable parameters that we have considered

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