Application of chemometrics, pls, to second-order derivative spectrophotometric determination of benzene as impurity in ethanol and isopropyl alcohol.
- In: SIG Quality of Pharmaceuticals - Poster Session
- At: Cairo (Egypt) (2005)
- Type: Poster
- Poster code: QP-P-008
- By: WAHBI, Abdelaziz (University of Alexandria, Pharm. Analytical Chemistry, Alexandria, Egypt)
- Co-author(s): Hassan (University of Alexandria, ALEXANDRIA, Egypt)
Fahmy (University of Alexandria, ALEXANDRIA, Egypt)
Hamdy (University of Alexandria, ALEXANDRIA, Egypt)
Benzene is assayed as an impurity in ethanol, I and isopropyl alcohol, II at a level of 2 ppm using GC methods (B.P. 2004) . The multivariate method of analysis (PLS) has been applied to develop a rapid, simple and direct spectrophotometric method for this purpose. Second-order derivative data has been recorded for I and II in 5 cm and 1 cm.. The access to the whole abstract and if available the presentation file is available to FIP members and to congress participants of that specific congress.