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Liposomal 5-fluorouracil for topical drug delivery

  • At: 2005 FIP Congress in Cairo (Egypt)
  • Type: Poster
  • By: NOUNOU, Mohamed Mahmoud (Pharmacy Faculty, Alexandria University, Department of Pharmaceutics, Alexandria, Egypt)
  • Co-author(s): El-Khordagui (Pharmacy Faculty, Alexandria University, ALEXANDRIA, Egypt)
    Khalafallah (Pharmacy Faculty, Alexandria University, ALEXANDRIA, Egypt)
    Khalil (Pharmacy Faculty, Alexandria University, ALEXANDRIA, Egypt)
  • Abstract:

    Effective topical therapy with 5-fluorouracil (5-FU) requires sustained availability of the drug at a minimum effective concentration in deeper skin layers with minimal systemic absorption. A liposomal 5-FU delivery system may fulfill such requirements although it presents formulation challenges because of the drug hydrophilicity and low molecular ..

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Last update 4 October 2019

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