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In search of active azatyrosinamide metabolites as anti-angiogenesis agents

  • In: SIG Pharmaceutical Biotechnology - Poster Session
  • At: Cairo (Egypt) (2005)
  • Type: Poster
  • Poster code: PB-P-005
  • By: WANG, Hui-Po (Chang Gung Universtiy, Graduate Institute of Natural Products, Tao-yuan, China Taiwan)
  • Co-author(s): Wen (Chang Gung Universtiy, Tao-Yuan, China Taiwan)
    Hsiu (China Medical University, Taichung, China Taiwan)
    Wen (China Medical University, Taichung, China Taiwan)
    Guh (National Taiwan University, Taipei, China Taiwan)
  • Abstract:

    HPW98-1, asynthesized in this laboratory, showed inhibitory activities on the growth of human colon, pancreatic and prostate cancer cells. It also demonstrated anti-angiogenesis effect in nude mice with VEGF-induced angiogenesis. As this compound exhibited short half-life, it is suspected that the antitumor activity might be resulted from its


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Last update 4 October 2019

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