Complexation of celecoxib and meloxicam with 2-hydroxy propyl beta-cyclodextrin using different techniques
- At: 2005 FIP Congress in Cairo (Egypt)
- Type: Poster
- By: KAMEL, Ola (Amriya, Research and product development, Alexandria, Egypt)
- Co-author(s): Mortada (Faculty of Pharmacy, ALEXANDRIA, Egypt)
El Maradny (Faculty of Pharmacy, ALEXANDRIA, Egypt)
Hikal (Amriya, ALEXANDRIA, Egypt)
The effect of hydroxypropyl ß-cyclodextrin (HPB) on the aqueous solubility and dissolution of celecoxib and meloxicam was investigated. Solid complexes were prepared by freeze drying, evaporation, and kneading. Various ratios of drug to HPB were prepared ranging from 1:1 up to 1:10. The resulting complexes were characterized using differential.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.