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Preparation and in vivo efficacy of insulin-containing enteric microspheres

  • At: 2010 FIP Congress in Lisbon (Portugal)
  • Type: Poster
  • By: CHANG, Li-Chien (National Defense Medical Center, Taipei, China Taiwan)
  • Co-author(s): Chio, Yi-Chen (National Defense Medical Center, TAIPEI, China Taiwan)
    Chua, Anna Chian New (National Defense Medical Center, TAIPEI, China Taiwan)
  • Abstract:

    Purpose: This work is to evaluate the feasibility of combining cell-penetrating peptide (CPP) and enteric coating strategies for oral insulin delivery. Methods: The CPP-modified insulin was synthesized by covalent linkage of a cell-penetrating peptide-low molecular weight protamine (LMWP) with insulin. Insulin and the modified insulin were..

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Last update 4 October 2019

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