Menu
  • Join
  • Login
  • Contact
 

Search abstracts


Syntheses of diclofenac-?-cyclodextrin hydrate conjugate for colon specific drug delivery

  • At: 2010 FIP Congress in Lisbon (Portugal)
  • Type: Poster
  • By: VIEIRA, Amélia (Faculty of Pharmacy, University of Coimbra, Coimbra, Portugal)
  • Co-author(s): Serra, Arménio (Chymiotechnon, Department of Chemistry, University of Coimbra, COIMBRA, Portugal)
    Carvalho, Rui (Department of Life Sciences and Centre for Neuroscience and Cell Biology, COIMBRA, Portugal)
    Gonçalves, Alexandra (Chymiotechnon, Department of Chemistry, University of Coimbra, COIMBRA, Portugal)
    Figueiras, Ana (Health Sciences Research Center, University of Beira Interior, Covilha, COVILHÃ, Portugal)
    Gonsalves, António (Chymiotechnon, Department of Chemistry, University of Coimbra, COIMBRA, Portugal)
    Veiga, Francisco (Faculty of Pharmacy, University of Coimbra, COIMBRA, Portugal)
  • Abstract:

    Purpose: The aim of this work was to prepare β-cyclodextrin prodrug of diclofenac (Dic).  For this purpose, the carboxylic group of Dic was esterified with hydroxyl groups of β-cyclodextrin hydrate (CD). Synthesis: Two principal strategies for establishing a covalent bonding between Dic and CD were attempted. The product identification was

    ..

  • The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress. Please login
Last update 4 October 2019

FIP Congresses