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Pulsatile release of bambuterol using novel ph-sensitive polymeric systems

  • At: Lisbon (Portugal) (2010)
  • Type: Poster
  • By: LEE, Beom-Jin (Kangwon National University, Chuncheon, South-Korea)
  • Co-author(s): Tran, Phuong (Kangwon National University, CHUNCHEON, South-Korea)
    Tran, Thao (Kangwon National University, CHUNCHEON, South-Korea)
    Park, Young Min (Kangwon National University, CHUNCHEON, South-Korea)
    Choe, Jae Seung (Eura Pharm. Inc.,, SUWON, South-Korea)
    Kim, Ji Tae (Eura Pharm. Inc.,, SUWON, South-Korea)
    Kim, Young Choong (Seoul National University, SEOUL, South-Korea)
    Chung, Kyu Hyuck (Sungkyunkwan University, SUWON, South-Korea)
  • Abstract:

    The aims of this work were to design pH-sensitive pulsatile drug delivery system which exposes an "on/off"pulse release of drug. Bambuterol to treat asthma was selected as a model drug. Binary blends of polyacrylic acid (PAA) and ethyl cellulose (EC) with different ratios were used for coatings as pH sensitive polymeric systems. PAA, a


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Last update 4 October 2019

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