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Interaction between corticosteroids and tacrolimus in kidney transplant patients

  • At: 2010 FIP Congress in Lisbon (Portugal)
  • Type: Poster
  • By: LALIC, Jelena (Pharmacy Department, Medical Faculty of Nis, Nis, Yugoslavia)
  • Co-author(s): Catic -Djordjevic, Aleksandra (Pharmacy Department, Medical Faculty of Nis, NIS, Serbia)
    Velickovic -Radovanovic, Radmila (Pharmacy Department, Medical Faculty of Nis, NIS, Serbia)
    Cvetkovic, Tatjana (Pharmacy Department, Medical Faculty of Nis, NIS, Serbia)
    Paunovic, Goran (Clinic of nephrology and haemodialysis, Clinical centre Nis, NIS, Serbia)
    Djodjevic, Vidojko (Medical faculty of Nis, NIS, Serbia)
  • Abstract:

    Introduction: Tacrolimus (TAC) is a potent immunosuppressant widely used in kidney transplantation for prophylaxis of organ rejection. Monitoring of TAC concentration is of utmost importance due to its narrow therapeutic index, variable pharmacokinetics and interactions with medicines. Corticosteroids (CS) are inductors of CYP3A4 enzyme which

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Last update 4 October 2019

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