Population pharmacokinetics of 3-ap
- At: 2010 FIP Congress in Lisbon (Portugal)
- Type: Poster
- By: KOLESAR, Jill (University of Wisconsin, Madison, United States of America)
Purpose:The purpose of this study was to develop a population pharmacokinetic (PK) model for 3-AP pharmacokinetics and to evaluate the effect of ABCB1 polymorphisms on the pharmacokinetic profile of 3-AP and to assess the relationship between 3AP disposition and patient covariates. Methods: A total of 40 patients with advanced cancer from two.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.