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Enhancement of biofilm formation by subinhibitory macrolides in icaadbc-positive and -negative clinical isolates of staphylococcus epidermidis

  • At: 2010 FIP Congress in Lisbon (Portugal)
  • Type: Poster
  • By: QIAN, Wang (The Third Military Medical University, Chongqing, China)
  • Co-author(s): Fengjun, Sun (The Third Military Medical University, CHONGQING, China)
    Yao, Liu (The Third Military Medical University, CHONGQING, China)
    Lirong, Xiong (The Third Military Medical University, CHONGQING, China)
    Linli, Xie (The Third Military Medical University, CHONGQING, China)
    Peiyuan, Xia (The Third Military Medical University, CHONGQING, China)
  • Abstract:

    Biofilm formation in Staphylococcus epidermidis is mediated by icaADBC-dependent and -independent pathways. The icaADBC operon involves the production of polysaccharide intercellular adhesin. Of 125 clinical isolates of S. epidermidis, 87% (105) isolates were resistant to macrolide antibiotics. Subinhibitory erythromycin, azithromycin and..

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Last update 4 October 2019

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