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Preparation of silymarin-loaded solid dispersion with enhanced solubility using pvp k30, tween 80 and water

  • At: 2010 FIP Congress in Lisbon (Portugal)
  • Type: Poster
  • By: YONG, Chul Soon (College of Pharmacy, Yeungnam University, Gyeongsan-si, South-Korea)
  • Co-author(s): Yang, Kwanyeol (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Yeo, Woohyun (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Yi, Jeong-Hun (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Cho, Jung Hyun (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
    Seo, Youngee (College of Pharmacy, Yeungnam University, GYEONGSAN-SI, South-Korea)
  • Abstract:

    To design a novel silymarin-loaded solid dispersion with enhanced solubility, various silymarin-loaded solid dispersions were prepared with water, polyvinylpyrrolidone (PVP) K30 and Tween 80, employing surface-attached method. The optimized carrier was selected by solubility and dissolution tests. The effects of PVP K30 and Tween 80 on the aqueous ..

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Last update 4 October 2019

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