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Facilitated skin permeation of buspirone microemulsions by electrically assisted method

  • At: 2010 FIP Congress in Lisbon (Portugal)
  • Type: Poster
  • By: WU, Pao-Chu (School of Pharmacy, Kaohsiung Medical University, Kaohsiung, China Taiwan)
  • Co-author(s): Chang, Jung Tzu (School of Pharmacy, Kaohsiung Medical University, KAOHSIUNG, China Taiwan)
    Chang, Jui-Sheng (School of Pharmacy, Kaohsiung Medical University, KAOHSIUNG, China Taiwan)
    Huang, Chi-Te (School of Pharmacy, Kaohsiung Medical University, KAOHSIUNG, China Taiwan)
    Tsai, Yi-Hung (School of Pharmacy, Kaohsiung Medical University, KAOHSIUNG, China Taiwan)
  • Abstract:

    Buspirone hydrochloride is an orally administered anxiolytic drug. The usual oral dosage of buspirone in clinical treatment is 5-20 mg, 3 times /day. The half-life is about 2 -3 h and the absolute bioavailability is low at approximately 4%. Hence a transdermal system would provide an alternative way to bypass disadvantages of the oral route. In..

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Last update 4 October 2019

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