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Pharmacokinetic and pharmacodynamic properties of thioredoxin by fused to human serum albumin.

  • At: 2010 FIP Congress in Lisbon (Portugal)
  • Type: Poster
  • By: OTAGIRI, Masaki (Fac. of Pharm. Sciences, Sojo Univ./Grad. Sch. of Pharm. Sciences, Kumamoto Univ, Kumamoto, Japan)
  • Co-author(s): Ikuta, Shotaro (Kumamoto University, KUMAMOTO, Japan)
    Ishima, Yu (Kumamoto University, KUMAMOTO, Japan)
    Furukawa, Masato (Kumamoto University, KUMAMOTO, Japan)
    Watanabe, Hiroshi (Kumamoto University, KUMAMOTO, Japan)
    Maruyama, Toru (Kumamoto University, KUMAMOTO, Japan)
    Chuang, Victor (Curtin University of Technology, PERTH, Australia)
  • Abstract:

    Thioredoxin-1 (Trx) is an approximately 12 kDa molecular weight protein that regulates extra- and intra-cellular redox mechanisms. It contains a highly conserved site (-Cys-Gly-Pro-Cys-) and scavenges reactive oxygen species. It has been reported to have antioxidant and antiinflammatory effects, and protective effects against a variety of..

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Last update 4 October 2019

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