Pharmacokinetic and pharmacodynamic properties of thioredoxin by fused to human serum albumin.

• In: Pharmaceutical Biotechnology Posters
• At: Lisbon (Portugal) (2010)
• Type: Poster
• Poster code: PB-P-001
• By: OTAGIRI, Masaki (Fac. of Pharm. Sciences, Sojo Univ./Grad. Sch. of Pharm. Sciences, Kumamoto Univ, Kumamoto, Japan)
• Co-author(s): Ikuta, Shotaro (Kumamoto University, KUMAMOTO, Japan)
  Ishima, Yu (Kumamoto University, KUMAMOTO, Japan)
  Furukawa, Masato (Kumamoto University, KUMAMOTO, Japan)
  Watanabe, Hiroshi (Kumamoto University, KUMAMOTO, Japan)
  Maruyama, Toru (Kumamoto University, KUMAMOTO, Japan)
  Chuang, Victor (Curtin University of Technology, PERTH, Australia)
  
• Abstract:

  Thioredoxin-1 (Trx) is an approximately 12 kDa molecular weight protein that regulates extra- and intra-cellular redox mechanisms. It contains a highly conserved site (-Cys-Gly-Pro-Cys-) and scavenges reactive oxygen species. It has been reported to have antioxidant and antiinflammatory effects, and protective effects against a variety of..

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