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Formulation and in vitro evaluation of theophylline matrix tablets prepared by direct compression: effect of polymer blends

  • At: 2010 FIP Congress in Lisbon (Portugal)
  • Type: Poster
  • By: EL-BAGORY, Ibrahim (King Saud University, College of Pharmacy, Dep. Pharmaceutics, Riyadh, Saudi Arabia)
  • Co-author(s): Barakat, Nahla (King Saud University, College of Pharmacy (Girls), Dep. Pharmaceutics, RIYADH, Saudi Arabia)
    Ibrahim, Mohamed (Kayyali Chair for Pharmaceutical Industries, King Saud University, RIYADH, Saudi Arabia)
    El-Enazi, Fouza (King Saud University, College of Pharmacy (Girls), Dept. of Pharmaceutics, RIYADH, Saudi Arabia)
  • Abstract:

    The deformation mechanism of pharmaceutical powders, used in formulating directly compressed matrix tablets, affects the characteristics of the formed tablets. Three polymers of different deformation mechanisms were tested for their impact on theophylline directly compressed tablets namely Kollidon ® SR (KL SR, plastic deformation),..

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Last update 4 October 2019

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