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Triptolide suppresses oxaliplatin-induced HSP70 in colon cancer and potentiates the growth inhibition of oxaliplatin in vitro and in vivo

  • At: 2010 FIP Congress in Lisbon (Portugal)
  • Type: Poster
  • By: XU, Jianhua (School of Pharmacy, Fujian Medical University, Fuzhou, China)
  • Co-author(s): Hu, Yingying (School of Pharmacy, Fujian Medical University, Fuzhou, China)
    Li, Wei (School of Pharmacy, Fujian Medical University, Fuzhou, China)
    Chen, Yuanzhong (Fujian Institute of Hematology, Fujian Medical University, Fuzhou, China)
    Huang, Xiuwang (School of Pharmacy, Fujian Medical University, Fuzhou, China)
  • Abstract:

    Background: To evaluate the anti-cancer potential of triptolide alone or in combination with oxaliplatin in colon cancer cells and xenograft models and to investigate the possible mechanisms. Methods: Human colon cancer SW480 cells were treated with triptolide and oxaliplatin alone or with their combination. Cell proliferation and apoptosis were

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Last update 4 October 2019

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