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Salbutamol sulfate in-situ nasal gelling systems: formulation and evaluation

  • At: 2010 FIP Congress in Lisbon (Portugal)
  • Type: Poster
  • By: ETMAN, Mohamed (Faculty of Pharmacy, University of Alexandria, Alexandria, Egypt)
  • Co-author(s): Farid, Ragwa (Faculty of Pharmacy and Drug manufacturing ,Pharos University, ALEXANDRIA, Egypt)
    Ebian, Abdel-Azim (Faculty of Pharmacy, University of Alexandria, ALEXANDRIA, Egypt)
    Nada, Aly (Faculty of Pharmacy, Kuwait University, SAFAT, Kuwait)
  • Abstract:

    Introduction: Oral salbutamol undergoes first-pass metabolism. Nasal delivery could protect drugs from this effect. Mucoadhesive in-situ gels for salbutamol sulfate (SS) with gellan gum were formulated and tested in rats.

    Methods: SS in-situ gels (2% w/w) were prepared at concentration of gellan gum 0.2%, 0.4% and 0.8% w/v with methyl paraben..

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Last update 4 October 2019

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