Surface-charged flexosomes for enhanced skin delivery of temoporfin

• At: 2009 FIP Congress in Istanbul (Turkey)
• Type: Poster
• By: DRAGICEVIC-CURIC, Nina (Apoteka Beograd, Belgrade, Yugoslavia)
• Co-author(s): Winter, Sven (Ratiopharm GmbH, ULM, Germany)
  Gitter, Burkhard (Biolitec AG, JENA, Germany)
  Milosevic-Kostadinovic, Katarina (Apoteka Medicor, KOTOR, Montenegro)
  Fahr, Alfred (Lehrstuhl fuer Pharmazeutische Technologie, Friedrich-Schiller Universitaet Jena, JENA, Germany)
  
• Abstract:

  Purpose: Temoporfin (mTHPC) is a potent second-generation synthetic photo-sensitizer. For cutaneous malignant or non-malignant diseases, topical photodynamic therapy (PDT) would be advantageous. The aim of this study was to investigate the penetration enhancing ability of surface-charged mTHPC-loaded flexosomes.
  
  Methods: Different mTHPC (1.5..

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