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Influence of CYP2C19*2, CYP2C19*3 and CYP2C9*3 genotypes on anti-epileptic drugs resistance of refractory epileptics

  • At: 2009 FIP Congress in Istanbul (Turkey)
  • Type: Poster
  • By: JIANG, Dechun (Department of Pharmacy, Xuanwu Hospital of Capital Medical University, Beijing, China)
  • Co-author(s): Zhang, Qingxia (Department of Pharmacy, Xuanwu Hospital of Capital Medical University, Beijing, China)
    Wang, Yuqin (Department of Pharmacy, Xuanwu Hospital of Capital Medical University, Beijing, China)
  • Abstract:

    To study mechanism of drug resistance in refractory epilepsy. CYP2C19*2/*3 and CYP2C9*3 were detected by RFLP method. 96 patients with refractory epilepsy having received operation with resection of epileptogenic focus (A group) and 270 patients with non-refractory epilepsy responsive to monotherapy of antiepileptic drugs (B group) were collected.

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Last update 4 October 2019

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