Synthesis and pharmcological profiles of the anticholinergic agent, n-alkyl phencynonate and the optical isomers
- At: 2009 FIP Congress in Istanbul (Turkey)
- Type: Poster
- By: LIU, He (Beijing Institute of Pharmacology and Toxicology, Beijing, China)
The new anticholinergic agents,N-alkyl-9a-(3-Azabicyclo[3,3,1]nonanyl)-2
'-cyclopentyl-2'-hydroxy-2'-phenylacetate (CPG),were synthesized and the enantiomers were obtained by the optical resolution
of racemates with the chiral host N-p-toluenesulfonylglutamic acid. Optical pure isomers
were also effective diastereoselective synthesized using.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.