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Synthesis and pharmcological profiles of the anticholinergic agent, n-alkyl phencynonate and the optical isomers

  • At: 2009 FIP Congress in Istanbul (Turkey)
  • Type: Poster
  • By: LIU, He (Beijing Institute of Pharmacology and Toxicology, Beijing, China)
  • Abstract:

    The new anticholinergic agents,N-alkyl-9a-(3-Azabicyclo[3,3,1]nonanyl)-2

    '-cyclopentyl-2'-hydroxy-2'-phenylacetate (CPG),were synthesized and the enantiomers were obtained by the optical resolution

    of racemates with the chiral host N-p-toluenesulfonylglutamic acid. Optical pure isomers

    were also effective diastereoselective synthesized using..

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Last update 4 October 2019

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