Effect of formulation on substituting wet granulation with direct compression process for the industrial production of tablets with a high dose drug
- At: 2009 FIP Congress in Istanbul (Turkey)
- Type: Poster
- By: MALAJ, Ledjan (Department of Pharmacy, Faculty of Medicine, University of Tirana, Tirana, Albania)
- Co-author(s): Di Martino, Piera (Department of Chemical Sciences, University of Camerino, Camerino, Italy)
Background information: Metformine HCl is a high dose drug used in the treatment of type II diabetes. Due to its poor tabletability properties, tablets are produced by a wet granulation process. The objective of this study is to formulate direct compression metformine HCl tablets suitable for industrial process and coating operation. Methods:.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.