Effect of formulation on substituting wet granulation with direct compression process for the industrial production of tablets with a high dose drug

• At: 2009 FIP Congress in Istanbul (Turkey)
• Type: Poster
• By: MALAJ, Ledjan (Department of Pharmacy, Faculty of Medicine, University of Tirana, Tirana, Albania)
• Co-author(s): Di Martino, Piera (Department of Chemical Sciences, University of Camerino, Camerino, Italy)
  
• Abstract:

  Background information: Metformine HCl is a high dose drug used in the treatment of type II diabetes. Due to its poor tabletability properties, tablets are produced by a wet granulation process. The objective of this study is to formulate direct compression metformine HCl tablets suitable for industrial process and coating operation. Methods:

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