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Roles of mgo in solid dispersion systems containing weakly dibasic telmisartan

  • At: 2009 FIP Congress in Istanbul (Turkey)
  • Type: Poster
  • By: LEE, Beom-Jin (College of Pharmacy, Kangwon National University, Chuncheon, South-Korea)
  • Co-author(s): Tran, Phuong (College of Pharmacy, Kangwon National University, CHUNCHEON, South-Korea)
    Tran, Thao (College of Pharmacy, Kangwon National University, CHUNCHEON, South-Korea)
    Tran, Huyen (College of Pharmacy, Kangwon National University, CHUNCHEON, South-Korea)
    Lee, Kyung-Ho (College of Pharmacy, Kangwon National University, CHUNCHEON, South-Korea)
    Chun, Inkoo (College of Pharmacy, Dongduk Women’s University, SEOUL, South-Korea)
  • Abstract:

    The roles of MgO in three different solid dispersion (SD) systems: SD1 (drug, MgO and PEG 6000), SD2 (drug and PEG 6000) and SD3 (drug and MgO) containing the weakly dibasic model drug, telmisartan (TEL) were investigated. A binary SD2 without MgO showed the lowest TEL dissolution despite its structural amorphousness, but SD3 significantly..

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Last update 4 October 2019

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