Simultaneous determination of three quinoline antimalarials in human plasma using ultra-performance liquid chromatography–tandem mass spectrometric method

• At: 2009 FIP Congress in Istanbul (Turkey)
• Type: Presentations + Posters
• By: ABDEL-HAMID, Magdi (King Saud University, Riyadh, Saudi Arabia)
• Co-author(s): Alsarra, Ibrahim (King Saud University, Riyadh, Saudi Arabia)
  Alanazi, Fars (King Saud University, Riyadh, Saudi Arabia)
  
• Abstract:

  Chloroquine (CQ), primaquine (PQ) and quinine (QN) are quinoline compounds belonging to hemozoin inhibitors antimalarials. In KSA, the first line treatment for P. falciparum, P.vivax and P.ovale malaria cases involves a three day curative treatment, in the first and second days with CQ alone and with CQ and PQ in the third day. Later if no

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