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Preparation and stability study of two amorphous ergot derivative drugs

  • At: 2009 FIP Congress in Istanbul (Turkey)
  • Type: Poster
  • By: MALAJ, Ledjan (Department of Pharmacy, Faculty of Medicine, University of Tirana, Tirana, Albania)
  • Co-author(s): Gashi, Zehadin (Department of Pharmacy, Faculty of Medicine, University of Tirana, Tirana, Albania)
    Myftari, Brunilda (Department of Pharmacy, Faculty of Medicine, University of Tirana, Tirana, Albania)
    Shkreli, Rezarta (Department of Pharmacy, Faculty of Medicine, University of Tirana, Tirana, Albania)
    Di Martino, Piera (Department of Chemical Sciences, University of Camerino, Camerino, Italy)
  • Abstract:

    Background information: Nicergoline and cabergoline are two crystalline semisynthetic ergot derivatives insoluble in water. They are respectively used in the treatment of senile dementia and Parkinsonism. The preparation and the use of their amorphous forms instead of crystalline ones should enhance bioavailability. Because amorphous state is not

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Last update 4 October 2019

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