Quantitative determination of azithromycin in human plasma by liquid chromatography-tandem mass spectrometry and its application to a pharmacokinetic study
- At: 2009 FIP Congress in Istanbul (Turkey)
- Type: Poster
- By: WATTANANAT, Triporn (Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand)
- Co-author(s): Akarawut, Wiyada (Department of Medical Sciences, Ministry of Public Health, NONTHABURI, Thailand)
A simple, rapid and sensitive liquid chromatography-tandem mass spectrometric method was developed and validated for the determination of azithromycin in human plasma. Roxithromycin was used as an internal standard. The method utilized protein precipitation with acetonitrile. Separation was performed on a C18 column with a mobile phase of 50 mM.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.