Over expression of midkine retards disease progression and prolongs life span under the presence of the als stress.

• In: Clinical Biology - Posters
• At: Istanbul (Turkey) (2009)
• Type: Poster
• Poster code: CBS-P-001
• By: OKAMOTO, Mayumi (Waseda University, Tokyo, Japan)
• Co-author(s): Kato, Shinsuke (Tottori University, Faculty of Medicine, YONAGO, Japan)
  Umezu, Mitsuo (Waseda University, TOKYO, Japan)
  
• Abstract:

  ALS is a progressive fatal neurodegenerative disease characterized by degeneration of both upper and lower motor neurons. Midkine (MK) is a heparin binding growth factor. GCIs, which is histological hallmark of the multiple system atrophy, expressed MK. Based on this fact, we have focused on MK expression of the spinal cord in G1H-G93A mice. To..

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