Over expression of midkine retards disease progression and prolongs life span under the presence of the als stress.
- At: 2009 FIP Congress in Istanbul (Turkey)
- Type: Poster
- By: OKAMOTO, Mayumi (Waseda University, Tokyo, Japan)
- Co-author(s): Kato, Shinsuke (Tottori University, Faculty of Medicine, YONAGO, Japan)
Umezu, Mitsuo (Waseda University, TOKYO, Japan)
ALS is a progressive fatal neurodegenerative disease characterized by degeneration of both upper and lower motor neurons. Midkine (MK) is a heparin binding growth factor. GCIs, which is histological hallmark of the multiple system atrophy, expressed MK. Based on this fact, we have focused on MK expression of the spinal cord in G1H-G93A mice. To.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.