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The roles of ubiquitin-proteasome system, heat shock protein 70 and regulator of g protein signalling four in morphine-induced behavioural sensitization

  • At: Seville (Spain) (2022)
  • Type: Poster
  • Poster code: CBS-009
  • By: WANG, Yanting (Department of Pharmacy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, China)
  • Co-author(s): Dr Yanting Wang, Clinical Pharmacist (Department of Pharmacy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China)
    Ms. Xingzi Hou (State Key Laboratory of Natural and Biomimetic Drugs and Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, China)
    Dr. Shoupeng Wei (The Seventh Affiliated Hospital, Sun Yat-sen University, Shenzhen, China)
    Dr. Jiaqing Yan (Department of Pharmacy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China)
    Ms. Zhe Chen (Department of Pharmacy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China)
    Ms. Mingyu Zhang (Department of Pharmacy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China)
    Prof. Qingying Zhang (State Key Laboratory of Natural and Biomimetic Drugs and Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, China)
    Dr. Yingyuan Lu (State Key Laboratory of Natural and Biomimetic Drugs and Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University Health Science Center, Beijing, China)
    Ms. Qingjie Zhang (Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University, Beijing, China)
    Ms. Tiange Zheng (Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University, Beijing, China)
    Ms. Jingyi Jia (Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University, Beijing, China)
    Mr. Bin Dong (Department of Pharmacy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China)
    Ms. Ying Li (Department of Pharmacy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China)
    Ms. Yuanyuan Zhang (Department of Pharmacy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China)
    Prof. Jianhui Liang (Department of Molecular and Cellular Pharmacology, School of Pharmaceutical Sciences, Peking University, Beijing, China)
    Prof. Guohui Li (Department of Pharmacy, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China)
  • Abstract:

    Objective: Opioid addiction is a major public health issue, yet its underlying mechanism is still unknown. Several lines of evidence have indicated that ubiquitin-proteasome system (UPS), heat shock proteins and regulators of G protein singling were associated with opioid addiction. The aim of this study was to further explore the roles of UPS,..

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Last update 4 October 2019

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