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Development of a ranitidine controlled release gastroretentive oral dosage form

  • At: 2008 FIP Congress in Basel (Switzerland)
  • Type: Presentation
  • By: COELHO, Pedro (Universidade Fernando Pessoa, Porto, Portugal)
  • Co-author(s): Santos, Delfim (Faculdade de Farmácia U. Porto, Portugal)
    Bettini, Ruggero (Universitá Degli Studi di Parma, Italy)
    Colombo, Paolo (Universitá Degli Studi di Parma, Italy)
    Sonvico, Fabio (Universitá Degli Studi di Parma, Italy)
    Strusi, OrazioLuca (Universitá Degli Studi di Parma, Italy)
  • Abstract:

    Ranitidine is a very soluble drug which half life is approximately 3 hours and that due to its physicochemical characteristics is better absorbed in the stomach and upper duodenum. Due to its characteristics it is a good candidate for a controlled release, gastrorentetive oral administration. Hydrophilic matrices are an easy yet effective way of

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Last update 4 October 2019

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