Cell-based gene therapies in oncology: Case study of the challenges of CAR-T therapy

• At: 2019 FIP Congress in AbuDhabi (United Arab Emirates)
• Type: Presentation
• By: KOLESAR, Jill (University of Kentucky, USA)
• Abstract:

  CAR T therapy is a type of treatment in which a patient's T cells are removed via apheresis, sent to a processing laboratory and a chimeric antigen receptor (CAR) is introduced into the T cells, which allows the CAR T cell to identify and eliminate both malignant and normal cells that express a given antigen.   While multiple tumor antigens are

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