Comparative bioavailability of two brands of oral sustained-release nitroglycerin tablets
- At: 2008 FIP Congress in Basel (Switzerland)
- Type: Poster
- By: GHANDFOROUSH-SATTARI, Mohammadreza (Tabriz University of Medical Sciences, Tabriz, Iran)
- Co-author(s): Valizadeh, Hadi (Tabriz University of Medical Sciences, TABRIZ, Iran)
Zakeri, Parvin (Tabriz University of Medical Sciences, TABRIZ, Iran)
Mashayekhi, Siminozar (Hematology and Oncology Research Centre, Tabriz, Iran, Iran)
Nitroglycerin (GTN, glyceryl trinitrate) has been used in the treatment of angina pectoris for more than a century. Following oral administration, GTN undergoes extensive first pass hepatic metabolism, thus for the pharmacokinetic study of oral GTN, its main two stable metabolites; 1,2-dinitroglycerin (1,2-GDN) and 1,3-dinitroglycerin (1,3-GDN).. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.