DESIGN OF KAPPA OPIOID RECEPTOR MODULATORS USING SALVINORIN A AS A LEAD FOR ADDICTION MANAGEMENT.
- At: 2019 FIP Congress in AbuDhabi (United Arab Emirates)
- Type: Presentation
- By: SHOEMAKE, Claire (University of Malta, Pharmacy, Malta)
- Co-author(s): Maria Mangion: Pharmacy, University of Malta, Msida, Malta
Claire Shoemake: Pharmacy, University of Malta, Msida,
The Kappa Opioid Receptor (K-OR) was traditionally considered a target for analgesia. Studies have also shown its association with reward pathways making it a novel target for addiction management.Salvinorin A, (Salvia divinorum spp.), is the only known non-alkaloidal and selective K-OR full agonist.
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