DESIGN OF KAPPA OPIOID RECEPTOR MODULATORS USING SALVINORIN A AS A LEAD FOR ADDICTION MANAGEMENT.

• At: 2019 FIP Congress in AbuDhabi (United Arab Emirates)
• Type: Presentation
• By: SHOEMAKE, Claire (University of Malta, Pharmacy, Malta)
• Co-author(s): Maria Mangion: Pharmacy, University of Malta, Msida, Malta
  Claire Shoemake: Pharmacy, University of Malta, Msida,
  
• Abstract:

  Background

  The Kappa Opioid Receptor (K-OR) was traditionally considered a target for analgesia. Studies have also shown its association with reward pathways making it a novel target for addiction management. Salvinorin A, (Salvia divinorum spp.), is the only known non-alkaloidal and selective K-OR full agonist.

  Methods

  A dual approach- Virtual
  ..

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