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DESIGN OF KAPPA OPIOID RECEPTOR MODULATORS USING SALVINORIN A AS A LEAD FOR ADDICTION MANAGEMENT.

  • At: 2019 FIP Congress in AbuDhabi (United Arab Emirates)
  • Type: Presentation
  • By: SHOEMAKE, Claire (University of Malta, Pharmacy, Malta)
  • Co-author(s): Maria Mangion: Pharmacy, University of Malta, Msida, Malta
    Claire Shoemake: Pharmacy, University of Malta, Msida,
  • Abstract:

    Background

    The Kappa Opioid Receptor (K-OR) was traditionally considered a target for analgesia. Studies have also shown its association with reward pathways making it a novel target for addiction management.Salvinorin A, (Salvia divinorum spp.), is the only known non-alkaloidal and selective K-OR full agonist.

    Methods

    A dual approach- Virtual

    ..

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Last update 4 October 2019

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