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Development of a dry powder formulation for inhalation of poly(lactic-co-glycolic acid) microcapsules for sustained-release pulmonary delivery of insulin

  • At: 2008 FIP Congress in Basel (Switzerland)
  • Type: Presentation
  • By: HAMISHEHKAR, Hamed (Dep. Pharmaceutics, School of Pharmacy, Isfahan Medical Sciences University, Isfahan, Iran)
  • Co-author(s): Emami, Jaber (Dep. Pharmaceutics, School of Pharmacy, Isfahan Medical Sciences University, Isfahan, Iran)
    Rouholamini Najafabadi, Abdolhossein (Aerosol Research Lab., School of Pharmacy, Tehran University of Medical Sciences, Iran)
    Gilani, Kambiz (Aerosol Research Lab., School of Pharmacy, Tehran University of Medical Sciences, Iran)
    Minaiyan, Mohsen (Dep. Pharmacology, School of Pharmacy, Isfahan University of Medical Sciences, Isfahan, Iran)
    Mahdavi, Hamid (Dep. of Novel Drug Delivery Systems, Iran Polymer and Petrochemical Institute, Iran)
    Nokhodchi, Ali (Medway School of Pharmacy, The Universities of Kent and Greenwich, United Kingdom)
  • Abstract:

    Purpose. Dry powder inhalers (DPIs) mostly contain carrier based formulations where micronized drug particles are adhered to coarse carrier particles. An emphasis will be made in this study on investigating the morphology and surface characteristics of mannitol and sorbitol as the alternative carriers of traditionally used carrier, lactose, for

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Last update 4 October 2019

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