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PHARMACOKINETICS AND EFFICACY OF THE NEW PDE INHIBITOR MS54 IN ANIMAL MODELS OF AUTOIMMUNE DISEASES

  • At: 2019 FIP Congress in AbuDhabi (United Arab Emirates)
  • Type: Poster
  • By: WYSKA, Elzbieta (Jagiellonian University Medical College, Department of Pharmacokinetics and Physical Pharmacy, Poland)
  • Co-author(s): Elżbieta Wyska: Department of Pharmacokinetics and Physical Pharmacy, Jagiellonian University Medical College, Kraków, Poland
    Artur Świerczek: Department of Pharmacokinetics and Physical Pharmacy, Jagiellonian University Medical College, Kraków, Poland
    Krzysztof Pociecha: Department of Pharmacokinetics and Physical Pharmacy, Jagiellonian University Medical College, Kraków, Poland
    Marietta Ślusarczyk: Department of Medicinal Chemistry, Jagiellonian University Medical College, Kraków, Poland
    Grażyna Chłoń-Rzepa: Department of Medicinal Chemistry, Jagiellonian University Medical College, Kraków, Poland
  • Abstract:

    Background

    Autoimmune diseases (AID) are chronic disorders of unknown etiology, often leading to disability and premature mortality. In search for new therapeutic options, selective phosphodiesterase (PDE) inhibitors have been tested using animal models of these diseases, however, up to date, none of them has been registered for this indication.

    Meth

    ..

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Last update 21 September 2019

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