DEVELOPMENT OF A HOT MELT EXTRUDED FORMULATION BASED ON COMPUTATIONAL SIMULATION

• At: 2019 FIP Congress in AbuDhabi (United Arab Emirates)
• Type: Poster
• By: PARK, Jun-Bom (Sahmyook University, Pharmaceutics and Drug Delivery, Korea, Republic Of)
• Co-author(s): Jun-Bom Park: College of Pharmacy, Sahmyook University, Seoul, Korea, Republic Of
  Dong Hwan Sohn: College of Pharmacy, Keimyung University, Daegu, Korea, Republic Of
  Beom-Jin Lee: College of Pharmacy, Ajou University, Suwon, Korea, Republic Of
  
• Abstract:

  Background

  Model based drug development (MBDD) is a global trend in the pharmaceutical industry. Global big pharmaceutical companies are conducting combination MDBB to reduce clinical trial costs and efforts during development.

  Methods

  The in vitro dissolution test of cilostazol, a model drug, showed abnormally that the hot melt extrudate had a lower
  ..

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