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NOVEL PEPTIDE-BASED NANOVESICULAR FORMULATION OF AN ANTIPSYCHOTIC AGENT FOR TRANSDERMAL DELIVERY

  • At: 2019 FIP Congress in AbuDhabi (United Arab Emirates)
  • Type: Poster
  • By: MANIKKATH, Jyothsna (Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Pharmaceutics, India)
  • Co-author(s): Jyothsna Manikkath: Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, India
    Srinivas Mutalik: Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, India
  • Abstract:

    Background

    Asenapine maleate (ASP) is an atypical antipsychotic used clinically in the treatment of schizophrena and bipolar disorder. It is extensively metabolized in the liver, yielding an oral bioavailability of <2%.

    Methods

    Liposomes were prepared thin film hydration technique, followed by ultrasound-assisted size reduction. Fractional Factorial

    ..

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Last update 4 October 2019

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