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NOVEL PEPTIDE-BASED NANOVESICULAR FORMULATION OF AN ANTIPSYCHOTIC AGENT FOR TRANSDERMAL DELIVERY
- At: 2019 FIP Congress in AbuDhabi (United Arab Emirates)
- Type: Poster
- By: MANIKKATH, Jyothsna (Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Pharmaceutics, India)
- Co-author(s): Jyothsna Manikkath: Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, India
Srinivas Mutalik: Pharmaceutics, Manipal College of Pharmaceutical Sciences, Manipal Academy of Higher Education, Manipal, India
BackgroundAsenapine maleate (ASP) is an atypical antipsychotic used clinically in the treatment of schizophrena and bipolar disorder. It is extensively metabolized in the liver, yielding an oral bioavailability of <2%.
MethodsLiposomes were prepared thin film hydration technique, followed by ultrasound-assisted size reduction. Fractional Factorial.. The access to the whole abstract and the presentation file is available to FIP members and to congress participants of that specific congress.
Last update 13 May 2019