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EVALUATION AND FORMULATION OF LIQUISOLID COMPACTS OF KETOCONAZOLE USING CENTRAL COMPOSITE DESIGN

  • At: 2019 FIP Congress in AbuDhabi (United Arab Emirates)
  • Type: Poster
  • By: LUITEL, Anup (Kathmandu University, Department of Pharmacy, Nepal)
  • Co-author(s): Anup Luitel: Department of Pharmacy, Kathmandu University, Dhulikhel-4, Kavreplanchok, Nepal
    Uttam Budathoki: Department of Pharmacy, Kathmandu University, Dhulikhel-4, Kavreplanchok, Nepal
    Panna Thapa: Department of Pharmacy, Kathmandu University, Dhulikhel-4, Kavreplanchok, Nepal
  • Abstract:

    Background

    Ketoconazole is a broad-spectrum anti-fungal imidazole derivative, class II of BCS and exhibits poor aqueous solubility and high permeability is a 2nd generation drug indicated for different forms of candidoses.

    Methods

    Liquisolid compact was prepared using PEG 400(liquid vehicle), MCC PH 102(carrier material) and Aerosil 200(coating

    ..

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Last update 13 May 2019

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