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DESIGN, ONE POT SYNTHESIS, ANTICANCER ACTIVITY OF QUINAZOLINES AND MOLECULAR DOCKING STUDIES

  • At: 2019 FIP Congress in AbuDhabi (United Arab Emirates)
  • Type: Poster
  • By: RANI, Satla (jawaharlal nehru technological university hyderabad, centre for pharmaceutical sciences, institute of science and technology, India)
  • Co-author(s): Satla shobha Rani: centre for pharmaceutical sciences, institute of science and technology, jawaharlal nehru technological university hyderabad, HYDERABAD, India
    Raju Bathula: centre for pharmaceutical sciences, institute of science and technology, jawaharlal nehru technological university hyderabad, HYDERABAD, India
  • Abstract:

    Background

    One-pot synthesis of Substituted-1H-Pyrido[2,1-b] quinazoline derivatives by condensation of 2-aminopyrimidines, substituted aromatic aldehydes and ketones in the presence of ethanol by conventional reflux or by microwave synthesis using by catalyst. Quinazoline (4q) showed potent cytotoxicity in A549 and NCI-H460 lung cancer cell lines

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Last update 13 May 2019

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