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ANALYSIS DOXORUBICIN & DOXORUBICINOL IN DBS OF BREAST CANCER PATIENTS USING LC-MS:APPLICATION TO TDM

  • At: AbuDhabi (United Arab Emirates) (2019)
  • Type: Poster
  • Poster code: POS-ASP-003
  • By: HARAHAP, Yahdiana (Universitas Indonesia, Pharmacy, Indonesia)
  • Co-author(s): Yahdiana Harahap: Pharmacy, Universitas Indonesia, Depok, Indonesia
    Sabrina Nur Amalia: Pharmacy, Universitas Indonesia, Depok, Indonesia
    Aldhi Anarta: Pharmacy, Universitas Indonesia, Depok, Indonesia
    Herman Suryadi: Pharmacy, Universitas Indonesia, Depok, Indonesia
    Ramadhan Ramadhan: Dharmais Cancer Hospital, Jakarta, Indonesia
  • Abstract:

    Background

    The cardiotoxic effect of doxorubicin as first line chemotherapy agent of breast cancer is highly determined by accumulation of its main metabolite, doxorubicinol. Monitoring concentration of analyte and metabolite in DBS helps to prevent and minimize cardiotoxic effect by using ensuring appropriate dosage regiment with a more convenient

    ..

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Last update 28 September 2023

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