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Anti-tumor activity of novel fused pyrimidine and benzodiazepine analogues

  • At: 2018 FIP Congress in Glasgow (Scotland)
  • Type: Poster
  • By: A.SHALABY, Aya (Faculty of pharmacy, Mansoura University, Mansoura, Egypt)
  • Co-author(s):

    Heba M. El-Hadedy1, Aya   A. Shalaby* 1, Ghada S. Hassan2, Shahenda M. El-Messery2, Ahmed R. Elsheakh3

    1Faculty of Pharmacy, 2Department of pharmacutical organic chemistry, Faculty of pharmacy, 3Department of pharmacology and toxocology, Faculty of pharmacy, Mansoura University, Mansoura, Egypt

  • Abstract:


    In Egypt,

    • The most common cancer in women is breast cancer.
    • Unfortunately, it is also the 2nd leading cause of cancer death in women. 

    A series of benzo[b]pyrido[4,3-e][1,4]diazepines and benzo[4,5]thiazolo[3,2-a]pyrido[4,3-d]pyrimidines has been synthesized and tested for their in vitro antitumor activity against MCF -7 breast


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Last update 13 May 2019

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